Muscular Dystrophy is the weakening and loss of the muscle mass. An acute deficiency of dystrophin is the main reason for this occurrence of this disease. Duchenne muscular dystrophy is the most common type of muscular dystrophy which if not treated could be fatal. Stem cell therapyis the only way to combat this muscle degeneration disease.
Skeletal muscle is the most profuse tissues in the human body and the main promoter of movement. They contain mature muscle cells that differentiate into myoblast. This myoblast merges together to form multinucleated muscle fibers that help in the formation or shaping of skeletal muscle. The genetic factors Muscular Dystrophy cause structural abnormalities and damage of muscle cells and even waning of the muscle fibers. This sudden weakening and loss of muscle stem cells, and systemic muscle atrophy in patients may lead to death due to respiratory or heart failure.
Like other degenerative neural and muscular disorders, DMD is the result of the loss of healthy cells essential for the normal functioning of the body. In the case Muscular Dystrophy, the absence or mutation of vital muscle protein leads to advanced degeneration of muscle leading to loss of stamina and limb deformities. However, stem cell therapy for Muscular Dystrophy has offered an encouraging hope to patients.
At well-known Neurogen clinics in India, patients with Muscular Dystrophy are treated with mesenchymal stem cells that are found in the bone marrow of the patients. These bone marrow derived cells have the ability to replace the damaged muscle with healthy tissues. In addition to the self-renewal, the mesenchymal stem cells also have the potential to differentiate and multiply into renewed muscles post stem cell transplantation.
For stem cell therapy for muscular dystrophy, the cells are procured from the patient’s own hip bone, with the help of a needle. They are then treated and are re-implanted into the muscle and spinal fluid of the patient.
These cells are supplied into the body in such a way that they get embedded within the muscles to secrete cytokines, improve the blood circulation and repair the damaged muscle cells. Cytokines also help in the repair of the damaged muscle membrane, improves the level of functional protein, repair the injured nerves, reduce muscle cells lesions, and boost the functions of the muscles. The development and differentiation properties of the stem cells help in the formation of new healthy muscle fibers by replacing the original atrophy of muscle. Thus, muscular dystrophy treatment with stem cells can improve the muscle strength by replacing the damaged cells.
A lot of improvement has been monitored in an MD patient after a neural treatment. Request for muscular dystrophy treatment with stem cell treatment has seen a steep rise in India. This treatment has proved to be beneficial for treating ischemic lower limb vascular disease, osteonecrosis, spinal cord injury, spinal cord injury and other serious diseases with a curative effect.
Stem cell therapy has created a revolution in the world of medicine. It is a treatment where the patient is operated upon with minimal incisions and his very own stem cells.